Dry powder inhalers: Mechanistic evaluation of lactose formulations containing salbutamol sulphate

The purpose of this study was to evaluate the relationships between physicochemical properties and aerosolisation performance of different grades of lactose. In order to get a wide range of physicochemical properties, various grades of lactose namely Flowlac® 100 (FLO), Lactopress anhydrous® 250 (LAC), Cellactose® 80 (CEL), Tablettose® 80 (TAB), and Granulac® 200 (GRA) were used. The different lactose grades were carefully sieved to separate...