Ali Nokhodchi
University of Sussex
Nuclear chemistrySolubilityControlled releaseNanotechnologyOrganic chemistryChemistryParticle sizeMaterials scienceCrystallizationDry-powder inhalerLactoseDrug deliveryDrugSolventDifferential scanning calorimetryChemical engineeringChromatographyPolymerDosage formDissolution
328Publications
63H-index
7,503Citations
Publications 328
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#1Shahla Mirzaeei (Kermanshah University of Medical Sciences)H-Index: 8
#2Mahla Mansurian (Kermanshah University of Medical Sciences)
Last. Ali Nokhodchi (University of Sussex)H-Index: 63
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The purpose of this study was to prepare poly (D-L) lactide-co-glycolide (PLGA) and poly e-caprolactone (PCL) nanofibers containing metronidazole and amoxicillin using an electrospinning process as intrapocket sustained-release drug delivery systems for the treatment of periodontal diseases. Scanning electron microscopy showed that the drug containing PLGA and PCL nanofibers produced from the electrospinning process was uniform and bead-free in morphology. The obtained nanofibers had a strong st...
1 CitationsSource
#1Golnar Rahimzadeh (Mazandaran University of Medical Sciences)H-Index: 4
#2Majid Saeedi (Mazandaran University of Medical Sciences)H-Index: 24
Last. Ali Nokhodchi (University of Sussex)H-Index: 63
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The therapeutic effectiveness of a chitosan encapsulated bacteriophage cocktail as a smart biocontrol agent was evaluated in this study to be used as a preventative and treatment option for gastrointestinal infections. To evaluate the effect of the bacteriophage formulation on the treatment of gastrointestinal infection, rats were infected with Salmonella enterica, Shigella flexneri, and Escherichia coli. The rats were weighed and their stools cultured. The results showed that the group which ha...
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#1Maryam Moazeni (Mazandaran University of Medical Sciences)H-Index: 13
#2Amirhossein Davari (Mazandaran University of Medical Sciences)H-Index: 3
Last. Ali Nokhodchi (University of Sussex)H-Index: 63
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Abstract Background An essential oil derived from the evergreen plant Thymus vulgaris acts as an antifungal agent with strong antimicrobial activity, but it has low water solubility. The current study therefore aimed to enhance the solubility of thyme essential oil by formulating it into a nanoemulsion and investigating its effectiveness on a broad range of fungi. Method The identification of the compositions of essential oils was performed using GC-MS. Thyme essential oil nanoemulsions (TV EO-N...
2 CitationsSource
#1Katayoun Morteza-Semnani (Mazandaran University of Medical Sciences)H-Index: 23
#2Majid Saeedi (Mazandaran University of Medical Sciences)H-Index: 24
Last. Ali Nokhodchi (University of Sussex)H-Index: 63
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Essential oils have been proposed as promising non-toxic transdermal permeation enhancers. Their use is limited because of their low water solubility. The use of nanotechnology-based strategies is one of the ways to overcome this limitation. This study aimed to explore the transdermal permeation enhancing capability of cumin essential oil in nanoemulgel systems containing diclofenac sodium. Cumin essential oil nanoemulsion was produced by high-pressure homogenization technique. The formulation w...
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#1Jafar Akbari (Mazandaran University of Medical Sciences)H-Index: 18
#2Majid Saeedi (Mazandaran University of Medical Sciences)H-Index: 24
Last. Ali Nokhodchi (University of Sussex)H-Index: 63
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The purpose of this research was to enhance the transdermal delivery of diclofenac sodium niosomal formulations. To characterise the obtained niosomes, SEM, XRPD, DSC and ATR-FTIR were employed. . The size of the niosomes increased from 158.00 ± 6.17 to 400.87 ± 4.99 nm when cholesterol was incorporated into the formulations. It was observed that the zeta potential of niofenac varies from -25.40 ± 1.352 to -43.13 ± 1.171 mV when the cholesterol percentage decreased from 2% to 0.2%. The higher en...
1 CitationsSource
#1Matthew LamH-Index: 3
#2Nour NashedH-Index: 1
Last. Ali NokhodchiH-Index: 63
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The Liqui-Mass technology (also known as Liqui-Pellet technology) has shown promising results in terms of enhancing the drug release rate of water insoluble drugs in a simplistic approach. However, there is no current study on sustained-release formulation using the Liqui-Mass technology. In this study, an attempt was made to produce a sustained-release Liqui-Tablet for the first time using a matrix-based approach. The non-volatile co-solvent used in the investigation included Tween 80, Tween 20...
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#1Jiawei Wang (University of Texas at Austin)
#2Yu Zhang (University of Texas at Austin)H-Index: 5
Last. Mohammed Maniruzzaman (University of Texas at Austin)H-Index: 21
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Abstract The ‘one-size-fits-all’ approach followed by conventional drug delivery platforms often restricts its application in pharmaceutical industry, due to the incapability of adapting to individual pharmacokinetic traits. Driven by the development of additive manufacturing (AM) technology, three-dimensional (3D) printed drug delivery medical devices have gained increasing popularity, which offers key advantages over traditional drug delivery systems. The major benefits include the ability to ...
3 CitationsSource
#1Maryam Maghsoodi (Tabriz University of Medical Sciences)H-Index: 12
#2Ali Nokhodchi (University of Sussex)H-Index: 63
Last. Hadi Pourasghari Azar (Tabriz University of Medical Sciences)
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Objective null The purpose of the present study was firstly to identify the effectiveness of Eudragit® polymers (Eudragit® RL, RS, L100-55, L100, S100 and E100) in inhibition of celecoxib precipitation from buffer solutions (pH =6.8). Furthermore, the influence of Eudragit® polymers on non-sink dissolution behavior of celecoxib from solid dispersions was investigated. null Methods null Solid dispersions were prepared by the rotary evaporation method. In vitro dissolution studies, FT-IR and diffe...
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#1Deck Khong TanH-Index: 5
#2Ali NokhodchiH-Index: 63
Last. Niko MünzenriederH-Index: 26
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