Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease
Abstract
Emerging evidence suggests beneficial effects of estrogen and estrogen-like chemicals on neurodegenerative diseases, especially Parkinson's disease (PD). Genistein, an isoflavone naturally found in soy products, displays estrogenic properties. The present study aims to investigate the neuroprotective effects of genistein on dopaminergic neurons in ovariectomized (OVX), 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD model mice....
Paper Details
Title
Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease
Published Date
Feb 1, 2008
Journal
Volume
60
Issue
2
Pages
156 - 161
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History