Making Individualized Decisions in the Midst of Uncertainties: The Case of Prostate Cancer and Biochemical Recurrence

The decision about whether to pursue aggressive treatment is one of the most common decisions in all of oncology, and it always includes uncertainties, patient preferences, and priorities. Often patients and physicians must make this decisionwithout guidance from randomized trial data. Even when trials have been conducted and demonstrated an overall benefit from an aggressive treatment, patients and physicians still must decide whether a benefit...