Abstract null null Background null Transperineal magnetic resonance imaging–transrectal ultrasound fusion guided biopsy (MFGB) is an increasingly popular technique due to increasing rates of biopsy-related infections. However, its widespread implementation has been hampered by the supposed necessity of epidural or general anesthesia. null null null Objective null To demonstrate the technique, feasibility, and results of transperineal MFGB under local anesthesia, in an ambulatory setting without ...
#2Enrico Checcucci(EAU: European Association of Urology)H-Index: 22
Last. Cristian Fiori(UNITO: University of Turin)H-Index: 37
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Abstract null null Background null Despite technical and technological innovations, percutaneous puncture still represents the most challenging step when performing percutaneous nephrolithotomy. This maneuver is characterized by the steepest learning curve and a risk of injuring surrounding organs and kidney damage. null null null Objective null To evaluate the feasibility of three-dimensional mixed reality (3D MR) holograms in establishing the access point and guiding the needle during percutan...
#2Martin Pichler(The University of Texas MD Anderson Cancer Center)H-Index: 61
Last. Renate Pichler(MUI: Innsbruck Medical University)H-Index: 21
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c-Met inhibition has direct antitumor effects on proliferation, angiogenesis, and metastasis, and indirect antitumor effects via prevention of the induction of immunosuppressive mechanisms (PD-L1, TGFβ, IDO1). c-Met inhibition is key to overcome resistance to immune checkpoint inhibition and to maximize the efficacy of immunotherapy.
#2Kamran Ahmed(KCL: King's College London)H-Index: 65
Last. Prokar Dasgupta(Guy's and St Thomas' NHS Foundation Trust)H-Index: 78
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BACKGROUND It is hypothesised that simulation enhances progression along the initial phase of the surgical learning curve. OBJECTIVE To evaluate whether residents undergoing additional simulation, compared to conventional training, are able to achieve proficiency sooner with better patient outcomes. DESIGN, SETTING, AND PARTICIPANTS This international, multicentre, randomised controlled trial recruited 94 urology residents with experience of zero to ten procedures and no prior exposure to simula...
Abstract null null Background null The taxanes docetaxel and cabazitaxel prolong overall survival for men with metastatic castration-resistant prostate cancer (mCRPC), with cabazitaxel approved in the postdocetaxel setting only. Recent data suggest they have similar efficacy but a different safety profile in the first-line mCRPC setting. null null null Objective null To assess patient preference between docetaxel and cabazitaxel among men who received one or more doses of each taxane and did not...
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