Inhibition of miR-92a improves re-endothelialization and prevents neointima formation following vascular injury
Abstract
AimsMicroRNA (miR)-92a is an important regulator of endothelial proliferation and angiogenesis after ischaemia, but the effects of miR-92a on re-endothelialization and neointimal lesion formation after vascular injury remain elusive. We tested the effects of lowering miR-92a levels using specific locked nucleic acid (LNA)-based antimiRs as well as endothelial-specific knock out of miR-92a on re-endothelialization and neointimal formation after...
Paper Details
Title
Inhibition of miR-92a improves re-endothelialization and prevents neointima formation following vascular injury
Published Date
Jun 27, 2014
Journal
Volume
103
Issue
4
Pages
564 - 572
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