Original paper
A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth
Abstract
Tumor metastasis accounts for 90% of cancer-associated deaths and is almost inaccessible by chemotherapy, surgical operation or radiotherapy. Here, a tumor metastasis-specific nanocarrier system has been constructed by modification of stealth lipid nanoparticles with a specific peptide ligand. Highly metastatic breast cancer MDA-MB-231 that stably expressed luciferase (MDA-MB-231/Luc) was used as tumor cell model. The nanocarrier was very...
Paper Details
Title
A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth
Published Date
Jan 1, 2013
Journal
Volume
34
Issue
3
Pages
756 - 764
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Notes
History