Targeting transcription factor STAT3 for cancer prevention and therapy

Volume: 162, Pages: 86 - 97
Published: Jun 1, 2016
Abstract
Signal Transducers and Activators of Transcription (STATs) comprise an important class of transcription factors that have been implicated in a wide variety of essential cellular functions related to proliferation, survival, and angiogenesis. Among various STAT members, STAT3 is frequently overexpressed in tumor cells as well as tissue samples, and regulates the expression of numerous oncogenic genes controlling the growth and metastasis of tumor...
Paper Details
Title
Targeting transcription factor STAT3 for cancer prevention and therapy
Published Date
Jun 1, 2016
Volume
162
Pages
86 - 97
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