Original paper
Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease
Abstract
Oxyntomodulin is a hormone and a growth factor. It activates two receptors, the Glucagon-like peptide 1 (GLP-1) and the glucagon receptor. GLP-1 mimetics are on the market as treatments for type 2 diabetes and are well tolerated. These drugs have shown neuroprotective properties in animal models of neurodegenerative disorders. In addition, the GLP-1 mimetic exendin-4 has shown protective effects in animal models of Parkinson's disease (PD), and...
Paper Details
Title
Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease
Published Date
Oct 1, 2015
Volume
765
Pages
284 - 290
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Notes
History