Development and in vitro/in vivo evaluation of a novel targeted polymeric micelle for delivery of paclitaxel
Volume: 80, Pages: 29 - 40
Published: Sep 1, 2015
Abstract
In this study a novel receptor-targeted micelle delivery system based on tocopherol succinate-chitosan-polyethylene glycol-folic acid (TS-CS-PEG-FA) was synthesized and loaded with paclitaxel (PTX). Physicochemical properties of the micelles such as critical micelle concentration, micelle size, entrapment efficiency, stability, release properties, cellular uptake and in vitro cytotoxicity were investigated in detail. Furthermore, the...
Paper Details
Title
Development and in vitro/in vivo evaluation of a novel targeted polymeric micelle for delivery of paclitaxel
Published Date
Sep 1, 2015
Volume
80
Pages
29 - 40
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