Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context

Volume: 33, Issue: 12, Pages: 2464 - 2483.e18
Published: Dec 1, 2021
Abstract
Mitochondria are key organelles for cellular energetics, metabolism, signaling, and quality control and have been linked to various diseases. Different views exist on the composition of the human mitochondrial proteome. We classified >8,000 proteins in mitochondrial preparations of human cells and defined a mitochondrial high-confidence proteome of >1,100 proteins (MitoCoP). We identified interactors of translocases, respiratory chain, and ATP...
Paper Details
Title
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Published Date
Dec 1, 2021
Volume
33
Issue
12
Pages
2464 - 2483.e18
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