AD-linked R47H- TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation
Abstract
R47H- TREM2 mutation enhances AKT signaling in human AD microglia and mediates proinflammatory and synaptic toxicity in a tauopathy mouse...
Paper Details
Title
AD-linked R47H- TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation
Published Date
Dec 1, 2021
Volume
13
Issue
622
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