Short-Course Induction Chemotherapy Followed by Radiotherapy is the Effective Strategy for Intermediate-Risk/High-Risk Early-Stage ENKTCL

This case of extranodal NK/T cell lymphoma (ENKTCL) without lymph nodes and distant organs involvement1 is consistent with Extended-stage I (with PTI, or primary tumor invasion). Short course (2-3 cycles) chemotherapy (CT) followed by radiotherapy (RT) may be the optimal choice.2,3 Either RT first or CT first resulted in comparable survival in the combined modality therapy setting, but CT response may be used to select patients who can be...