Microtubule Targeting Agents in Disease: Classic Drugs, Novel Roles
Abstract
Microtubule-targeting agents (MTAs) represent one of the most successful first-line therapies prescribed for cancer treatment. They interfere with microtubule (MT) dynamics by either stabilizing or destabilizing MTs, and in culture, they are believed to kill cells via apoptosis after eliciting mitotic arrest, among other mechanisms. This classical view of MTA therapies persisted for many years. However, the limited success of drugs specifically...
Paper Details
Title
Microtubule Targeting Agents in Disease: Classic Drugs, Novel Roles
Published Date
Nov 12, 2021
Journal
Volume
13
Issue
22
Pages
5650 - 5650
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Notes
History