Original paper
Repeated exposure with short-term behavioral stress resolves pre-existing stress-induced depressive-like behavior in mice
Abstract
Chronic stress induces adaptive changes in the brain via the cumulative action of glucocorticoids, which is associated with mood disorders. Here we show that repeated daily five-minute restraint resolves pre-existing stress-induced depressive-like behavior in mice. Repeated injection of glucocorticoids in low doses mimics the anti-depressive effects of short-term stress. Repeated exposure to short-term stress and injection of glucocorticoids...
Paper Details
Title
Repeated exposure with short-term behavioral stress resolves pre-existing stress-induced depressive-like behavior in mice
Published Date
Nov 18, 2021
Journal
Volume
12
Issue
1