Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFβ signaling
Abstract
Emerging evidence shows the association between nuclear envelope and tumor progression, however, the functional contributions of specific constituents of the nuclear envelope remain largely unclear. We found that the expression level of transmembrane protein 201 (TMEM201), an integral inner nuclear membrane protein of unknown function, was significantly elevated in invasive breast cancer and predicted poor breast cancer prognosis. We showed that...
Paper Details
Title
Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGFβ signaling
Published Date
Nov 19, 2021
Journal
Volume
41
Issue
5
Pages
647 - 656
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