Vancomycin recognition and induced-aggregation of the Au nanoparticles through freeze-thaw for foodborne pathogen Staphylococcus aureus detection

Infectious diseases caused by foodborne pathogens have become a serious public health problem. It is urgent to develop simple, rapid, and visual methods for pathogen detection. Herein, gold nanoparticles (AuNPs), aptamer and vancomycin (Van) based dual-recognition molecules and magnetic enrichment were combined to realize visual detection of Staphylococcus aureus (S. aureus). Initially, S. aureus was bounded to aptamer coupled Fe3O4 with high...