Original paper
Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products
Abstract
Helminth parasites are adept manipulators of the immune system, using multiple strategies to evade the host type 2 response. In the intestinal niche, the epithelium is crucial for initiating type 2 immunity via tuft cells, which together with goblet cells expand dramatically in response to the type 2 cytokines IL-4 and IL-13. However, it is not known whether helminths modulate these epithelial cell populations. In vitro, using small intestinal...
Paper Details
Title
Intestinal epithelial tuft cell induction is negated by a murine helminth and its secreted products
Published Date
Nov 15, 2021
Volume
219
Issue
1