Targeting c-Met to Improve Immune Checkpoint Inhibition in Metastatic Renal Cell Carcinoma
Abstract
c-Met inhibition has direct antitumor effects on proliferation, angiogenesis, and metastasis, and indirect antitumor effects via prevention of the induction of immunosuppressive mechanisms (PD-L1, TGFβ, IDO1). c-Met inhibition is key to overcome resistance to immune checkpoint inhibition and to maximize the efficacy of...
Paper Details
Title
Targeting c-Met to Improve Immune Checkpoint Inhibition in Metastatic Renal Cell Carcinoma
Published Date
Jan 1, 2022
Journal
Volume
81
Issue
1
Pages
1 - 2
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Notes
History