CXCL12/SDF-1 in IgG4-Related Disease

Volume: 12
Published: Oct 26, 2021
Abstract
Background: SDF-1/CXCL12 is a chemokine with pleiotropic functions in hematopoietic stem cell niche homeostasis, germinal center architecture, B cell maturation, neoangiogenesis, and fibrosis. Recently, the CXCL12/CXCR4/CXCR7 axis was associated with cancer metastasis and autoimmune diseases. The IgG4-related disease (IgG4-RD) is a pathological condition characterized by IgG4+ plasma cells infiltrating fibrotic lesions. The aim of this research...
Paper Details
Title
CXCL12/SDF-1 in IgG4-Related Disease
Published Date
Oct 26, 2021
Volume
12
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