Pretreatment Platelet Count and Neutrophil/Lymphocyte Ratio Are Predictive Markers for Carboplatin Plus Pemetrexed Therapy-induced Thrombocytopenia
Abstract
This study aimed to identify the predictive markers for carboplatin-induced severe thrombocytopenia.We conducted a retrospective cohort analysis of inpatients who received carboplatin and pemetrexed.Among the 106 eligible patients, the incidence rate of grade ≥3 thrombocytopenia was 29.2% (31/106). Multivariate analysis revealed that grade ≥3 thrombocytopenia was associated with platelet count ≤26.6×104/mm3 [odds ratio (OR)=24.70, 95% confidence...
Paper Details
Title
Pretreatment Platelet Count and Neutrophil/Lymphocyte Ratio Are Predictive Markers for Carboplatin Plus Pemetrexed Therapy-induced Thrombocytopenia
Published Date
Nov 1, 2021
Journal
Volume
41
Issue
11
Pages
5729 - 5737
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