The involvement of JAK/STAT signaling pathway in the treatment of Parkinson's disease
Abstract
Parkinson's disease (PD) is a neurodegenerative disorder in which inflammation and oxidative stress play key etiopathological role. The pathology of PD brain is characterized by inclusions of aggregated α-synuclein (α-SYN) in the cytoplasmic region of neurons. Clinical evidence suggests that stimulation of pro-inflammatory cytokines leads to neuroinflammation in the affected brain regions. Upon neuroinflammation, the Janus Kinase/Signal...
Paper Details
Title
The involvement of JAK/STAT signaling pathway in the treatment of Parkinson's disease
Published Date
Dec 1, 2021
Journal
Volume
361
Pages
577758 - 577758
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