High-throughput functional characterization of protein phosphorylation sites in yeast
Abstract
Phosphorylation is a critical post-translational modification involved in the regulation of almost all cellular processes. However, fewer than 5% of thousands of recently discovered phosphosites have been functionally annotated. In this study, we devised a chemical genetic approach to study the functional relevance of phosphosites in Saccharomyces cerevisiae. We generated 474 yeast strains with mutations in specific phosphosites that were...
Paper Details
Title
High-throughput functional characterization of protein phosphorylation sites in yeast
Published Date
Oct 18, 2021
Journal
Volume
40
Issue
3
Pages
382 - 390
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History