Original paper
Molecular profiling of pediatric and adolescent ependymomas: identification of genetic variants using a next-generation sequencing panel
Abstract
Ependymoma (EPN) accounts for approximately 10% of all primary central nervous system (CNS) tumors in children and in most cases, chemotherapy is ineffective and treatment remains challenging. We investigated molecular alterations, with a potential prognostic marker and therapeutic target in EPNs of childhood and adolescence, using a next-generation sequencing (NGS) panel specific for pediatric neoplasms. We selected 61 samples with initial...
Paper Details
Title
Molecular profiling of pediatric and adolescent ependymomas: identification of genetic variants using a next-generation sequencing panel
Published Date
Sep 27, 2021
Journal
Volume
155
Issue
1
Pages
13 - 23
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Notes
History