Pineal Parenchymal Tumors of Intermediate Differentiation Treated With Ventricular Radiation and Temozolomide

The pineal gland is a small, pinecone-shaped midline circumventricular organ that produces melatonin. It is located posterior to the third ventricle and is embryologically derived from an outpouching of its ependyma. Tumors of the pineal region are rare, composing less than 1% of intracranial neoplasms.1 They typically present with symptoms secondary to mass effect on nearby structures. Compression of the cerebral aqueduct results in...