Abstract null null Introduction null Respiratory motion management strategies, specifically motion-encompassing methods, in radiation therapy typically assume reproducible breathing. In reality, respiratory motion variations occur and ultimately cause tumor motion variations, which can result in differences between the planned and delivered dose distributions. Therefore, breathing guidance techniques have been investigated to improve respiratory reproducibility. To our knowledge, bi-level positi...
Abstract null null Neoadjuvant chemoradiotherapy followed by lobectomy is thought to increase survival in patients with Stage IIIa non-small cell lung cancer. Bronchopleural fistula is a rare complication of lung surgery. A 48-year-old female presented with adenocarcinoma of the left upper lobe. She underwent neoadjuvant radiotherapy of 60Gy in 30 fractions with concurrent cisplatin and etoposide followed by lobectomy, revealing a complete pathological response. Subsequent surveillance CTs showe...
Abstract null null Purpose null While intensity modulated proton therapy can deliver simultaneous integrated boost (SIB) to the dominant intraprostatic lesion (DIL) with high precision, it is sensitive to anatomic changes. We investigated the dosimetric effects from these changes based on pretreatment cone-beam computed tomographic (CBCT) images and identified the most important factors using a multilayer perceptron neural network (MLPNN). null null null Methods and Materials null DILs were cont...
Abstract null null Herein, we report a novel technique of combination of Rotte “Y” applicator and standard tandem (three-channel) brachytherapy (BT) for endometrial cancer (EC). We treated an older adult patient with medically inoperable EC using radiation therapy (RT) alone. External beam radiation therapy (EBRT) was administered, followed by four sessions of brachytherapy. However, there was insufficient dosimetric coverage of the uterine body in the first two conventional Rotte Y applicator B...
#1Victoria Y. Yu(MSK: Memorial Sloan Kettering Cancer Center)H-Index: 3
#2Kristen L. Zakian(MSK: Memorial Sloan Kettering Cancer Center)H-Index: 27
Last. Ricardo Otazo(MSK: Memorial Sloan Kettering Cancer Center)H-Index: 27
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Abstract null null Purpose null To assess the impact of a combination of compressed sensing and SENSE acceleration techniques on radiation therapy MRI simulation workflows. null null null Methods null 37 acquisitions were performed with both SENSE-only (SENSE) and combined compressed sensing and SENSE (CS) techniques in 24 patients receiving radiotherapy MRI simulation for a wide range of disease sites. The anatomic field of view prescription and image resolution were identical for both SENSE an...
#1Ulysses G Gardner(JHUSOM: Johns Hopkins University School of Medicine)
#2Stephanie G. Wood(OHSU: Oregon Health & Science University)H-Index: 2
Last. Aaron J. Grossberg(OHSU: Oregon Health & Science University)H-Index: 16
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Abstract null null Background null Patients with Fanconi anemia (FA) have a 50-fold higher likelihood of developing malignancies, specifically of the head and neck region and digestive tract. The standard of care for these cancers, specifically of the aero-digestive tract, typically include chemotherapeutics and radiation therapy which interfere with DNA crosslinking. These agents are usually avoided in FA due to mutations in the Fanconi anemia pathway leading to DNA repair instability. null nul...
Last. Bill J. Salter(UofU: University of Utah)H-Index: 20
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Abstract null null Purpose null A modern radiation oncology electronic medical record (RO-EMR) system represents a sophisticated human-computer interface with the potential to reduce human driven errors and improve patient safety. As the RO-EMR becomes an integral part of clinical processes, it may be advantageous to analyze learning opportunities (LO) based on their relationship with the RO-EMR. This work reviews one institution's documented LO to: (1) study their relationship with the RO-EMR w...
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