Insights into modifiable risk factors of cholelithiasis: A Mendelian randomization study

Background and Aims The risk factors of cholelithiasis have not been clearly identified, especially for total cholesterol. Here, we try to identify these causal risk factors. Approach and Results We obtained genetic variants associated with the exposures at the genome‐wide significance ( p < 5 × 10 −8 ) level from corresponding genome‐wide association studies. Summary‐level statistical data for cholelithiasis were obtained from FinnGen and UK...