Immunization With RANKL Inhibits Osteolytic Bone Metastasis in Breast Cancer.
Abstract
Breast cancer cells often metastasize to bone. Accumulating evidence suggests that inhibiting the receptor activator of nuclear factor-κB ligand (RANKL) not only leads to reduced bone metastasis of breast cancer but also has antitumoral effects. Here, we used mutant receptor activator of nuclear factor-κB ligand (RANKLM) as a vaccine for active immunization to induce antibodies for immunotherapy of bone metastatic cancer. We investigated whether...
Paper Details
Title
Immunization With RANKL Inhibits Osteolytic Bone Metastasis in Breast Cancer.
Published Date
Sep 21, 2021
Journal
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Notes
History