m6A modification of circHPS5 and hepatocellular carcinoma progression through HMGA2 expression
Abstract
N6-methyladenosine (m6A) is capable of mediating circRNA generation in carcinoma biology. Nevertheless, the posttranscriptional systems of m6A and circRNA in hepatocellular carcinoma (HCC) development are still unclear. The present study identified a circRNA with m6A modification, circHPS5, which was increased in neoplasm HCC tissues and indicated poor patient survival. Silencing of circHPS5 inhibited epithelial-mesenchymal transition (EMT) and...
Paper Details
Title
m6A modification of circHPS5 and hepatocellular carcinoma progression through HMGA2 expression
Published Date
Dec 1, 2021
Volume
26
Pages
637 - 648
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