Mitochondrial sirtuins genetic variations and gastric cancer risk: Evidence from retrospective observational study
Abstract
The purpose of the present study was to analyze the role of selected polymorphisms of SIRT3 and SIRT5 in gastric carcinogenesis.For this study, 500 blood samples of GC patients and 500 blood samples of healthy individuals were collected. Six selected polymorphisms of mitochondrial sirtuins were analyzed for analysis using Tetra-Arms PCR followed by DNA sequencing.Mutant allele frequencies of selected polymorphisms [rs3782116 (p < 0.0001),...
Paper Details
Title
Mitochondrial sirtuins genetic variations and gastric cancer risk: Evidence from retrospective observational study
Published Date
Jan 1, 2022
Journal
Volume
807
Pages
145951 - 145951
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