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#1Kavita Sharma (Jamia Millia Islamia)
#2Prithvi Singh (Jamia Millia Islamia)H-Index: 3
Last. Mansoor Ali Syed (Jamia Millia Islamia)H-Index: 18
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Abstract null null Epidemiological studies have established that untreated hypertension (HTN) is a major independent risk factor for developing cardiovascular diseases (CVD), stroke, renal failure, and other conditions. Several important studies have been published to prevent and manage HTN; however, antihypertensive agents' optimal choice remains controversial. Therefore, the present study is undertaken to update our knowledge in the primary treatment of HTN, specifically in the setting of othe...
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#1Rebecca T. Kimball (UF: University of Florida)H-Index: 40
#2Marissa Guido (UF: University of Florida)
Last. Edward L. Braun (UF: University of Florida)H-Index: 52
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Abstract null null Mitochondrial sequences were among the first molecular data collected for phylogenetic studies and they are plentiful in DNA sequence archives. However, the future value of mitogenomic data in phylogenetics is uncertain, because its phylogenetic signal sometimes conflicts with that of the nuclear genome. A thorough understanding of the causes and prevalence of cyto-nuclear discordance would aid in reconciling different results owing to sequence data type, and provide a framewo...
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#1Emily P.Y. Yu (U of O: University of Ottawa)
#2Sofia Perin (U of O: University of Ottawa)H-Index: 4
Last. Marc Ekker (U of O: University of Ottawa)H-Index: 51
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Abstract null null The homeodomain-containing transcription factors dlx1a, dlx2a, dlx5a and dlx6a are expressed in the zebrafish brain in overlapping patterns and are important in vertebrate development. Previous work in mice have suggested the overlapping expression pattern is in part due to cross-regulatory interactions among the aforementioned dlx genes. However, the extent of these interactions and whether they are conserved among vertebrates remains to be determined. Through whole-mount in ...
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#1zeynab aliyari serej (Tabriz University of Medical Sciences)H-Index: 4
#2Ayyub Ebrahimi (Haliç University)H-Index: 6
Last. Behzad Baradaran (Tabriz University of Medical Sciences)H-Index: 41
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Abstract null null In the treatment of breast cancer (BC), as an important type of cancer in women, the specific cells, called cancer stem cells (CSCs), are the reason of failure and metastasis. So, targeting CSCs can be used as a novel strategy in cancer therapy in addition to common therapeutic strategies. According to the importance of CSCs, we tried to find a correlation between stemness and metastatic characteristics of BC cells, to address whether CSCs are a potential target for cancer the...
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#1Nasrin N.A. Berruien (University of Westminster)
#2Joanne F. Murray (Edin.: University of Edinburgh)
Last. Caroline L. Smith (University of Westminster)H-Index: 10
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Abstract null null Selecting stably expressed reference genes which are not affected by physiological or pathophysiological conditions is crucial for reliable quantification in gene expression studies. This study examined the expression stability of a panel of twelve reference genes in tissues from the female mouse reproductive axis and the uterus. Gene expression studies were carried out using reverse transcriptase quantitative polymerase chain reaction (RT-qPCR). cDNA was synthesised from RNA ...
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Last. Qing ZhangH-Index: 3
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Abstract null null Objective null Both COVID-19 and influenza are viral respiratory tract infections and the epidemics of viral respiratory tract infections remain highly prevalent with lethal consequences in susceptible individuals. Expression of ICAM-1 on vascular endothelium recruits leukocytes which initiates inflammation. IL-6 induces ICAM-1. Both ICAM-1 and IL-6 can be enhanced in influenza virus infection and COVID-19 patients. Besides initiation of virus entry host cells, whether HA alon...
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#1Haoze Wang (Dalian Ocean University)H-Index: 4
#2Jun Cui (Hunan Normal University)
Last. Xiuli Wang (Dalian Ocean University)H-Index: 14
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Abstract null null Fish skeletal muscle is comprised of fast muscle (FM) and slow muscle (SM), which constitutes 60% of total the body mass. Fish skeletal muscle can affect fish swimming activity, which is important for aquaculture due to its growth-potentiating effects. DNA methylation can influence gene expression level. We previously identified multiple differentially expressed genes (DEGs) between FM and SM in Takifugu rubripes. However, it is unknown if the expression levels of these DEGs a...
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#1Meruyert Abdukassimova (NU: Nazarbayev University)
#2Perizat Kanabekova (NU: Nazarbayev University)
Last. Wassim Y. Almawi (NU: Nazarbayev University)H-Index: 43
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Abstract null null Background null Recurrent pregnancy loss (RPL) is major pregnancy complication, with poorly defined cause. Forkhead Box P3 (FOXP3) is a transcription factor that supports Treg activation and development and attenuates immune responses. As FOXP3 production is genetically determined, we tested the association of FOXP3 gene variants with RPL. null null null Methods null A retrospective case-control study, performed between April 2019 and February 2020. Study subjects comprised 62...
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#1Long Zhang (CWNU: China West Normal University)H-Index: 10
#2Haihong XiaoH-Index: 1
Last. Yan-Qiang TangH-Index: 1
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Defensins represent a family of cysteine-rich peptides that have broad-spectrum antimicrobial activities and serve as a typical kind of effector molecule in the immunity. Ruminant species have a large number of β-defensins in the absence of α- and θ-defensins. It is well-known that the genomes of sheep and cattle harbor at least 43 and 57 β-defensin genes, respectively. However, the repertoire of the goat β-defensin gene family has not been fully elucidated. In this study, we identified a total ...
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#1Pauline Raimondeau (University of Toulouse)H-Index: 1
#2Sophie Manzi (University of Toulouse)H-Index: 10
Last. Guillaume Besnard (University of Toulouse)H-Index: 49
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Abstract null null The betel nut (Areca catechu L., Arecaceae) is a monoecious cultivated palm tree that is widespread in tropical regions. It is mainly cultivated for producing areca nuts, from which seeds are extracted and chewed by local populations principally in the Indo-Pacific region. Seeds contain alkaloids which are central nervous system stimulants and are highly addictive. Wild relatives of the betel nut are distributed in South Asia and Australasia, with ca. 40-50 Areca species curre...
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