Understanding primary and secondary causes of liver failure after resection of peri-hilar cholangiocarcinoma

The surgical management and treatment of patients with perihilar cholangiocarcinoma (pCCA) remains one of the most challenging aspects of hepatopancreatobiliary oncology. Patients with pCCA face many perioperative obstacles, including physical deconditioning, biliary drainage of the future liver remnant, risk for cholangitis, determining the extent of hepatectomy, intraoperative margin assessment, and potential complications of biliary-enteric...