Flavio G. Rocha
Oregon Health & Science University
Survival analysisCancerInternal medicineSurgeryOncologyResectionPropensity score matchingEvidence-based medicineHepatectomyFOLFIRINOXToolboxImmunotherapyAdjuvant therapyCancer immunologyPancreasDiseaseMEDLINELiver transplantationSurgical oncologyPancreatic cancerImmunosuppressionTargeted therapyIntrahepatic CholangiocarcinomaEarly RecurrenceMultimodality TherapyTransplantationHigh morbidityAdjuvant chemotherapyRepeat hepatectomyCancer researchColorectal cancerCarcinogenesisBioinformaticsGeneral surgeryText miningMedicineGastroenterology
6Publications
1H-index
1Citations
Publications 7
Newest
#1Skye C. Mayo (OHSU: Oregon Health & Science University)H-Index: 25
#2Flavio G. Rocha (OHSU: Oregon Health & Science University)H-Index: 1
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#1David J. Bentrem (NU: Northwestern University)H-Index: 79
#2Flavio G. Rocha (OHSU: Oregon Health & Science University)H-Index: 1
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#1Yasmin Essaji (Virginia Mason Medical Center)
#2Flavio G. Rocha (OHSU: Oregon Health & Science University)H-Index: 1
Adjuvant therapy for pancreatic cancer has undergone a paradigm shift in the last 30 years. Before the 1990s, surgery was the main treatment with high morbidity and minimal long-term survival. In the mid-1980s, GITSG showed a doubling of overall survival from 11 to 20 months with 5-fluorouracil-based chemoradiation and now the PRODIGE trial showed the benefit of FOLFIRINOX with the longest overall survival to date approaching 5 years. Further investigation on the agents, duration and sequencing ...
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#1Bradley N. Reames (UNMC: University of Nebraska Medical Center)H-Index: 3
#2Flavio G. Rocha (OHSU: Oregon Health & Science University)H-Index: 1
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#1Flavio G. Rocha (OHSU: Oregon Health & Science University)H-Index: 1
1 CitationsSource
#1Jonathan J. HueH-Index: 3
#2Flavio G. Rocha (OHSU: Oregon Health & Science University)H-Index: 1
Last. Lee M. OcuinH-Index: 5
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BACKGROUND The main surgical approach to patients with localized intrahepatic cholangiocarcinoma (ICC) is hepatectomy, but transplantation has been described. A comparison of outcomes between these surgical approaches is necessary to determine if one is preferable. METHODS Patients with ICC were identified using the National Cancer Database (2010-2016). Patients were grouped based on operation and matched 1:1 by propensity score. Pathologic and postoperative outcomes, as well as overall survival...
3 CitationsSource
#1Flavio G. Rocha (OHSU: Oregon Health & Science University)H-Index: 1
Pancreatic cancer is one of the most aggressive gastrointestinal malignancies despite multimodality therapy. In the last several years, genomic studies have revealed that carcinogenesis is driven largely by key driver mutations that can be targeted for oncologic therapy. In addition, advances in cancer immunology have identified receptors and monoclonal antibodies that can be manipulated into harnessing the power of the host’s immune system for antitumor treatment. These strategies have generate...
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