FORMULATION AND EVALUATION OF SIMVASTATIN LOADED MICROEMULSION BASED GEL: IN VITRO CHARACTERIZATION

The Simvastatin loaded microemulsion based gel was formulated and in-vitro evaluation was done for the treatment of diabetic wound healing. Simvastatin is BCS class II drug which promotes wound healing by increasing the production of vascular endothelial growth factor (VEGF). Microemulsions (MEs) are oil and water colloidal system stabilized by the mixture of surfactant and co-surfactant offering enhance skin permeability for both hydrophobic...