Original paper
Allosteric activation of PP2A inhibits experimental abdominal aortic aneurysm
Abstract
Although extremely important, the molecular mechanisms that govern aortic aneurysm (AA) formation and progression are still poorly understood. This deficit represents a critical roadblock toward the development of effective pharmaceutical therapies for the treatment of AA. While dysregulation of protein phosphatase 2A (PP2A) is thought to play a role in cardiovascular disease, its role in aortic aneurysm is unknown. The objective of the present...
Paper Details
Title
Allosteric activation of PP2A inhibits experimental abdominal aortic aneurysm
Published Date
Sep 1, 2021
Journal
Volume
135
Issue
17
Pages
2085 - 2097
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Notes
History