Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task

Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO 2 (HDBR + CO 2 ) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. The addition of CO 2 to HDBR is thought to better mimic the conditions aboard the...