Background: In elite athletes, training individualization is widely recommended to optimize competitive performance. Previous studies have evidenced the impact of hormonal fluctuations on different performance parameters among women athletes. While consideration of menstrual cycle phases as a parameter in training individualization strategies is necessary, systematic evidence identifying such impacts in elite athletes should be evaluated. Objective: Systematically review publications that have i...
Introduction: Accounting for biological heterogeneity represents one of the greatest challenges in biomedical research. Dynamic computational and mathematical models can be used to enhance the study and understanding of biological systems, but traditional methods for calibration and validation generally do not account for the heterogeneity of biological data, resulting in overfitting and brittleness of these models. Herein we propose a machine learning approach that utilizes genetic algorithms t...
Last. Haiqun Cao(AAU: Anhui Agricultural University)H-Index: 13
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The olfactory system is used by insects to find hosts, mates, and oviposition sites. Insects have different types of olfactory proteins, including odorant-binding proteins (OBPs), chemosensory proteins (CSPs), odorant receptors (ORs), ionotropic receptors (IRs), and sensory neuron membrane proteins (SNMPs) to perceive chemical cues from the environment. The greater wax moth, Galleria mellonella, is an important lepidopteran pest of apiculture. However, the molecular mechanism underlying odorant ...
Background: Previous studies suggest that coronavirus disease 2019 (COVID-19) is a systemic infection involving multiple systems, and may cause autonomic dysfunction. Objective: To assess autonomic function and relate the findings to the severity and outcomes in COVID-19 patients. Methods: We included consecutive patients with COVID-19 admitted to the 21th COVID-19 Department of the east campus of Renmin Hospital of Wuhan University (a COVID-19-designated hospital) from 6 Feb to 7 Mar 2020. Clin...
Last. Nicholas Gant(University of Auckland)H-Index: 22
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Acute hypobaric hypoxia (HH) is a major physiological threat during high-altitude flight and operations. In military aviation, although hypoxia-related fatalities are rare, incidences are common and are likely underreported. Hypoxia is a reduction in oxygen availability, which can impair brain function and performance of operational and safety-critical tasks. HH occurs at high altitude, due to the reduction in atmospheric oxygen pressure. This physiological state is also partially simulated in n...