Original paper
Nrf2 expression in pancreatic stellate cells promotes progression of cancer
Volume: 321, Issue: 4, Pages: G378 - G388
Published: Oct 1, 2021
Abstract
It was previously identified that systemic Nrf2 deletion attenuates pancreatic cancer progression in a mutant K-ras/p53-expressing mouse model (KPC mouse). In this study, the type of cell that is responsible for the retarded cancer progression was elucidated. Human pancreatic cancers were first examined, and elevated expression of NRF2-target gene products in α-smooth muscle actin-positive cells was found, suggesting that pancreatic stellate...
Paper Details
Title
Nrf2 expression in pancreatic stellate cells promotes progression of cancer
Published Date
Oct 1, 2021
Volume
321
Issue
4
Pages
G378 - G388
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Notes
History