American Journal of Physiology-gastrointestinal and Liver Physiology
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#1Jan D. Huizinga (McMaster University)H-Index: 65
#2Amer Hussain (McMaster University)
Last. Ji-Hong Chen (McMaster University)H-Index: 15
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Our understanding of human colonic motility, and autonomic reflexes that generate motor patterns, has increased markedly through high-resolution manometry. Details of the motor patterns are emergin...
#1Chih-Hsiang Alexander Chan (University of Auckland)H-Index: 1
#2Zahra Aghababaie (University of Auckland)H-Index: 4
Last. Timothy Robert Angeli-Gordon (University of Auckland)H-Index: 1
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Gastric distension is known to affect normal slow wave activity and gastric function, but links between slow wave dysrhythmias and stomach function are poorly understood. Low--resolution mapping is unable to capture complex spatial properties of gastric dysrhythmias, necessitating the use of high-resolution mapping techniques. Characterizing the nature of these dysrhythmias has implications in the understanding of post-prandial function and the development of new mapping devices. In this two‑pha...
#1Erica Lafoz (University of Barcelona)H-Index: 7
#2Genís Campreciós (ISCIII: Carlos III Health Institute)H-Index: 5
Last. María L. Martínez-Chantar (ISCIII: Carlos III Health Institute)H-Index: 37
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In patients, advanced cirrhosis only regresses partially once the etiological agent is withdrawn. Animal models for advanced cirrhosis regression are missing. Lifestyle interventions (LI) have show...
#1Gaspar Peña-Münzenmayer (Austral University of Chile)H-Index: 2
#2Yusuke Kondo (Kyushu Dental University)H-Index: 12
Last. Marcelo A. Catalán (Austral University of Chile)H-Index: 1
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Ae4 transporters are critical for Cl- uptake across the basolateral membrane of acinar cells in the submandibular gland (SMG). Although required for fluid secretion, little is known about the physi...
#1Amy Stieler Stewart (NCSU: North Carolina State University)H-Index: 4
#2Cecilia Schaaf (NCSU: North Carolina State University)
Last. Liara M. Gonzalez (NCSU: North Carolina State University)H-Index: 10
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Intestinal ischemia is a life-threatening emergency with mortality rates of 50-80% due to epithelial cell death and resultant barrier loss.Loss of the epithelial barrier occurs in conditions includ...
#1Gregory O'Grady (University of Auckland)H-Index: 29
#2Armen A. Gharibans (University of Auckland)H-Index: 6
Last. Jan D. Huizinga (McMaster University)H-Index: 65
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Gastric peristalsis is critically dependent on an underlying electrical conduction system. Recent years have witnessed substantial progress in clarifying the operations of this system, including it...
We conducted single cell RNA sequencing on pancreas tissue from five individuals. We identified eleven unique cell clusters including a large population of dedifferentiated cells as well as two uni...
#1Farid Zreik (Tel Aviv Sourasky Medical Center)
#2Reshef Meshulam (Tel Aviv Sourasky Medical Center)
Last. Giris Jacob (Tel Aviv Sourasky Medical Center)H-Index: 10
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Background: Postprandial orthostasis activates mechanisms of cardiovascular homeostasis in order to maintain normal blood pressure (BP) and adequate blood flow to vital organs. The underlying mecha...
#1Joerg Ermann (Harvard University)H-Index: 25
#2Mederbek Matmusaev (Brigham and Women's Hospital)
Last. Donna Terenzio (Boehringer Ingelheim)H-Index: 2
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ABSTRACT Background and Aims : Mouse and human data implicates the NOD1 and NOD2 sensors of the intestinal microbiome and the associated signal transduction via the RIPK2 kinase as a potentially ke...
#1Sameer Tiwari (U of C: University of Calgary)H-Index: 7
#2Sharmin Begum (U of C: University of Calgary)H-Index: 8
Last. Kris Chadee (U of C: University of Calgary)H-Index: 34
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Goblet cells are specialized for the production and secretion of MUC2 glycoproteins that forms a thick layer covering the mucosal epithelium as a protective barrier against noxious substances and invading microbes. High MUC2 mucin biosynthesis induces endoplasmic reticulum (ER) stress and apoptosis in goblet cells during inflammatory and infectious diseases. Autophagy is an intracellular degradation process required for maintenance of intestinal homeostasis. In this study, we hypothesized that a...
Top fields of study
Small intestine
Diabetes mellitus
Cell biology