Single-cell transcriptome analysis of diffuse large B cells in cerebrospinal fluid of central nervous system lymphoma
Abstract
Diffuse large B cells in the cerebrospinal fluid (CSF-DLBCs) have offered great promise for the diagnostics and therapeutics of central nervous system lymphoma (CNSL) leptomeningeal involvement. To explore the phenotypic states of CSF-DLBCs, we analyzed the transcriptomes of more than one thousand CSF-DLBCs from six patients with CNSL diffuse large B-cell lymphoma (DLBCL) using Smart-seq2 single-cell RNA sequencing. CSF-DLBCs were defined based...
Paper Details
Title
Single-cell transcriptome analysis of diffuse large B cells in cerebrospinal fluid of central nervous system lymphoma
Published Date
Sep 1, 2021
Journal
Volume
24
Issue
9
Pages
102972 - 102972
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