Original paper
A systems‐level analysis highlights microglial activation as a modifying factor in common epilepsies
Abstract
Aims The causes of distinct patterns of reduced cortical thickness in the common human epilepsies, detectable on neuroimaging and with important clinical consequences, are unknown. We investigated the underlying mechanisms of cortical thinning using a systems‐level analysis. Methods Imaging‐based cortical structural maps from a large‐scale epilepsy neuroimaging study were overlaid with highly spatially resolved human brain gene expression data...
Paper Details
Title
A systems‐level analysis highlights microglial activation as a modifying factor in common epilepsies
Published Date
Aug 13, 2021
Volume
48
Issue
1