Long-Term Safety and Tolerability of BMP7 and HGF Gene Overexpression in Rabbit Cornea
Volume: 10, Issue: 10, Pages: 6 - 6
Published: Aug 12, 2021
Abstract
Tissue-targeted localized BMP7+HGF genes delivered into the stroma via nanoparticle effectively treats corneal fibrosis and rehabilitates transparency in vivo without acute toxicity. This study evaluated the long-term safety and tolerability of BMP7+HGF nanomedicine for the eye in vivo.One eye each of 36 rabbits received balanced salt solution (group 1, naïve; n = 12), naked vector with polyethylenimine-conjugated gold nanoparticles (PEI2-GNP;...
Paper Details
Title
Long-Term Safety and Tolerability of BMP7 and HGF Gene Overexpression in Rabbit Cornea
Published Date
Aug 12, 2021
Volume
10
Issue
10
Pages
6 - 6
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