B-PO05-208 PATHOGENIC VARIANTS AS A RED HERRING: A CASE OF PREMATURE VENTRICULAR CONTRACTION-TRIGGERED VENTRICULAR FIBRILLATION WITH AN INCIDENTAL PATHOGENIC VARIANT IN LMNA-ENCODED LAMIN A/C

Pathogenic variants in LMNA-encoded lamin A/C can cause cardiomyopathies and cardiac conduction abnormalities. While genetic testing is a hallmark diagnostic tool critical in assessing inherited arrhythmia syndromes and cardiomyopathies, careful variant interpretation is of utmost importance. Describe a case that highlights the ongoing need for caution when interpreting genetic test results for inherited arrhythmia syndromes and cardiomyopathies...