Michael J. Ackerman
Mayo Clinic
QT intervalInternal medicineEndocrinologyCardiologyPediatricsSudden cardiac deathBrugada syndromeCatecholaminergic polymorphic ventricular tachycardiaCardiomyopathyLong QT syndromeHypertrophic cardiomyopathyGenetic testingPopulationSudden deathAnesthesiaMutationGeneticsMedicineMissense mutationBiology
1,014Publications
144H-index
48.3kCitations
Publications 1030
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#1Evaldas Čiplys (Vilnius University)H-Index: 7
#2Tautvydas Paskevicius (U of A: University of Alberta)H-Index: 2
Last. Michael J. Ackerman (Mayo Clinic)H-Index: 144
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Calreticulin (CALR) is a highly conserved multifunctional chaperone protein primarily present in the endoplasmic reticulum, where it regulates Ca2+ homeostasis. Recently, CALR has gained special interest for its diverse functions outside the endoplasmic reticulum, including the cell surface and extracellular space. Although high-resolution structures of CALR exist, it has not yet been established how different regions and individual amino acid residues contribute to structural stability of the p...
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#1Konstantinos C. Siontis (Mayo Clinic)H-Index: 23
#2Kan Liu (Mayo Clinic)
Last. Michael J. Ackerman (Mayo Clinic)H-Index: 144
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Abstract null null Background null There is no established screening approach for hypertrophic cardiomyopathy (HCM). We recently developed an artificial intelligence (AI) model for the detection of HCM based on the 12‑lead electrocardiogram (AI-ECG) in adults. Here, we aimed to validate this approach of ECG-based HCM detection in pediatric patients (age ≤ 18 years). null null null Methods null We identified a cohort of 300 children and adolescents with HCM (mean age 12.5 ± 4.6 years, male 68%) w...
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#1Kathryn E. Tobert (Mayo Clinic)H-Index: 1
#2J. Martijn Bos (Mayo Clinic)H-Index: 32
Last. Michael J. Ackerman (Mayo Clinic)H-Index: 144
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Abstract null null Background null Within the last 5 years, cardiac society guidelines have begun to acknowledge shared decision making (SDM) for the athlete with sudden cardiac death–predisposing genetic heart diseases (GHDs), such as long QT syndrome (LQTS), and the possibility for that athlete’s return to play. Previously, international guidelines embraced a de facto disqualification for all such athletes including athletes with solely a positive genetic test in Europe. null null null Objecti...
1 CitationsSource
#1Kathryn E. TobertH-Index: 1
#2David J. TesterH-Index: 76
Last. Michael J. AckermanH-Index: 144
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#1Kathryn E. TobertH-Index: 1
#2J. M BosH-Index: 5
Last. Michael J. AckermanH-Index: 144
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