‘Pain‐free TRUS B’: a phase 3 double‐blind placebo‐controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography‐guided prostate biopsy (ANZUP 1501)
Abstract
To determine whether the addition of inhaled methoxyflurane to periprostatic infiltration of local anaesthetic (PILA) during transrectal ultrasonography-guided prostate biopsies (TRUSBs) improved pain and other aspects of the experience.We conducted a multicentre, placebo-controlled, double-blind, randomized phase 3 trial, involving 420 men undergoing their first TRUSB. The intervention was PILA plus a patient-controlled device containing either...
Paper Details
Title
‘Pain‐free TRUS B’: a phase 3 double‐blind placebo‐controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasonography‐guided prostate biopsy (ANZUP 1501)
Published Date
Jul 30, 2021
Journal
Volume
129
Issue
5
Pages
591 - 600
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