B-PO05-028 EXOME SEQUENCING HIGHLIGHTS THE POTENTIAL ROLE OF PRE-CLINICAL CARDIOMYOPATHIES IN THE PATHOGENESES OF UNEXPLAINED SUDDEN CARDIAC ARREST AND DEATH IN THE YOUNG

Sudden cardiac arrest (SCA) and sudden unexplained death (SUD) are feared sequelae of many genetic heart diseases (GHDs). In rare circumstances, pathogenic variants in cardiomyopathy-susceptibility genes may result in electrical instability leading to SCA/SUD before any structural manifestations of an underlying cardiomyopathy are evident. To determine the yield of pathogenic/likely pathogenic (P/LP) variants in strong evidence...