Original paper
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Abstract
Patients with bipolar disorder (BIP) have a high risk of cardiovascular disease (CVD), despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP remain largely unknown. We investigated polygenic overlap between BIP and CVD phenotypes, including CVD risk factors and coronary artery disease (CAD). We analyzed large genome-wide association studies of BIP ( n = 51,710) and CVD phenotypes ( n = 159,208–795,640), using...
Paper Details
Title
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Published Date
Jul 23, 2021
Journal
Volume
11
Issue
1
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Notes
History