Original paper
Whole-genome sequencing of single circulating tumor cells from neuroendocrine neoplasms
Abstract
Single-cell profiling of circulating tumor cells (CTCs) as part of a minimally invasive liquid biopsy presents an opportunity to characterize and monitor tumor heterogeneity and evolution in individual patients. In this study, we aimed to compare single-cell copy number variation (CNV) data with tissue and define the degree of intra- and inter-patient genomic heterogeneity. We performed next-generation sequencing (NGS) whole-genome CNV analysis...
Paper Details
Title
Whole-genome sequencing of single circulating tumor cells from neuroendocrine neoplasms
Published Date
Sep 1, 2021
Journal
Volume
28
Issue
9
Pages
631 - 644
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Notes
History