Original paper
Lactational polychlorinated biphenyls exposure induces epigenetic alterations in the Leydig cells of progeny rats
Abstract
The present study was designed to establish the epigenetic mechanisms by which lactational exposure to PCBs affects the Leydig cell function in progeny rats. The lactating dams were oral gavaged with different doses of PCBs [1, 2 and 5 mg/kg or corn oil ] and Leydig cells were isolated from the testes of progeny rats at postnatal day (PND) 60. We assessed the expression of transcription factors regulating steroidogenic machinery and the promoter...
Paper Details
Title
Lactational polychlorinated biphenyls exposure induces epigenetic alterations in the Leydig cells of progeny rats
Published Date
Jul 9, 2021
Journal
Volume
53
Issue
9
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Notes
History