Papers 5,357
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#2Qinjun WangH-Index: 2
Last. Xisheng WangH-Index: 4
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It has been reported that circular RNA hsa_circ_0074032 (circ_0074032) has a higher level in prostate cancer (PCa) tissues. However, the role and regulatory mechanism of circ_0074032 in PCa are still unknown. Circ_0074032 was overexpressed in PCa, and high circ_0074032 level was associated with worse PCa-related prognosis. Functionally, circ_0074032 silencing decreased xenograft tumour growth in vivo and induced cell apoptosis, curbed cell proliferation, migration and invasion in PCa cells in vi...
#1Xiaoying Dai (HKU: University of Hong Kong)
#2Fu Shi (HKU: University of Hong Kong)
Last. Lin Sm (HKU: University of Hong Kong)
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Y chromosome abnormalities are the leading cause of male infertility. The clinical detection of abnormalities is necessary for appropriate genetic counselling. This study describes the prevalence, distribution and characteristics of Y chromosome abnormalities, which should be considered in the clinical management of infertile males. A total of 121 patients with oligozoospermia, 120 with azoospermia and 88 normal individuals were recruited between June 2019 and July 2021. Y chromosome microdeleti...
#1Xuexia Liu (Qingdao University)H-Index: 5
#2Zi Teng (Qingdao University)
Last. Fu-Jun Liu (Qingdao University)H-Index: 11
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Human semen is a heterogeneous group containing a portion of low-motility sperm, which may determine the sperm quality evaluation. Abnormally expressed proteins in low-motility spermatozoa will be the candidates for sperm biology research. By comparing proteomes of high- or low-motility spermatozoa from the same semen of normal fertile men, 21 differentially expressed proteins were identified. Proteins with molecular chaperone function were significantly over-represented, of which HSPA1L and HSP...
#1Xu Wu (Anhui Medical University)H-Index: 1
#2Guodong Liu (Anhui Medical University)H-Index: 1
Last. Xiansheng Zhang (Anhui Medical University)H-Index: 8
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The main purpose of this systematic review and meta-analysis was to explore the association between uric acid (UA) and erectile dysfunction (ED). Databases including PubMed, Cochrane Library and Web of Science were retrieved to identify studies published in English up to 31 June 2021. We preregistered this meta-analysis in the PROSPERO (registration number CRD42021267035). Two independent authors extracted the relevant data from all enrolled articles. We evaluated the quality of enrolled studies...
#1Liu Shasha (SCU: Sichuan University)H-Index: 1
#2Bo Liu (SCU: Sichuan University)H-Index: 1
Last. Fuping Li (SCU: Sichuan University)H-Index: 5
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Cryopreservation of small quantities of human spermatozoa whilst maintaining adequate post-thawing motility has been found an essential challenge for male fertility preservation. Therefore, the study used an effective, and convenient rapid-freezing method to freeze small amounts of human spermatozoa by adding self-prepared cryoprotectant (SPC) without animal component. In the feasibility experiment, no significant differences in progressive motility, normal sperm morphology, vitality or DNA frag...
#1Bin Pan (WMU: Weifang Medical University)
#2Jie Yu (WMU: Weifang Medical University)
Last. Xiaoli Liu (WMU: Weifang Medical University)
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Prostate cancer is a heterogeneous disease with high incidence and mortality. The functional role of miR-886 has been reported in various cancers and its dysregulation in prostate cancer was also found. Whether miR-886 was involved in the development of prostate cancer remains unclear, which was explored. miR-886 was evaluated in prostate cancer by RT-qPCR, and its clinical value was also assessed. Additionally, the role of miR-886 in prostate cancer cells was assessed by MTT and transwell assay...
#1Vrinda Singla (PGIMER: Post Graduate Institute of Medical Education and Research)
#2Shikha Goyal (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 17
Last. Rakesh Kapoor (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 21
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Angiosarcomas are rare but highly aggressive malignancies originating from lymphatic or vascular endothelial cells and may arise from any site in the body. Angiosarcomas of the genitourinary tract, especially of seminal vesicle origin, are extremely rare with only five reported cases. Surgery forms the mainstay of therapy in localised disease while adjuvant therapies are still being refined. We present the case of a 40-year old gentleman who presented with lower urinary tract symptoms and, on ev...
#1Hany Mohammed Saad (Suez Canal University)H-Index: 1
#2Sameh Fayek GamalEl Din (Cairo University)H-Index: 5
Last. Ahmed Adel (Cairo University)H-Index: 3
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This study aimed to screen healthy individuals who contracted COVID-19 for erectile dysfunction (ED) and to determine the potential risk factors that can predict ED in these individuals. One hundred and seven cases versus 90 controls agreed to participate in the study. Two structured interviews with 1 month interval were conducted. All participants were evaluated by the validated Arabic version of the international index of erectile function (IIEF-5) and assessment of the psychological state by ...
#1Shivendra Kumar Bhalothia (College of Veterinary and Animal Sciences, Mannuthy)
#2J.S. Mehta (College of Veterinary and Animal Sciences, Mannuthy)H-Index: 2
Last. Ashok Kumar (CSWRI: Central Sheep and Wool Research Institute)
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Antioxidants are used to minimize oxidative stress during liquid semen storage. The main aim of current study was to elucidate effect of supplementing melatonin and canthaxanthin in Tris-based extender could enhance seminal quality of ram at 4°C up to 72 h. A total of 48 ejaculates were collected from breeding Magra rams (n = 8) and were preliminarily subjected for various macroscopic and microscopic semen evaluation tests. These ejaculates were pooled and divided into three equal aliquots. Two ...
#1Nelson Quilaqueo (UFRO: University of La Frontera)
#2Juana V. Villegas (UFRO: University of La Frontera)H-Index: 18
Endocrine disruptor chemicals are exogenous molecules that generate adverse effects on human health by destabilizing the homeostasis of endocrine system and affecting directly human reproductive system by inhibiting or activating oestrogenic or androgenic receptors. Endocrine disruptor chemicals generate transgenerational epigenetic problems, besides being associated with male infertility. Epidemiological data indicate that the increase in reproductive problems in males in the last 50 years is c...
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